Treatment of cephalosporin G acid production wastewater by resin adsorption method来源：水处理技术 作者: 阅读：73409 网友评论0条 Updated: 2011-02-18 17:21 Source: water treatment technology Author: Read: 73409 2010 0 comments
Abstract : In order to reduce the COD of cephalosporin G acid production wastewater and recover the available materials, the method of tandem adsorption of macroporous adsorption resin and ion exchange resin was used to treat the effects of different adsorbents on the treatment results. The results show that under the conditions of an adsorption rate of 2.0 BV ¡¤ h-1, a desorption rate of 0.8 BV ¡¤ h-1, and a 60% volume fraction of acetone in water as the desorbent, the BD-1 macroporous resin is first treated; Under the conditions of a desorption rate of 2.5 BV ¡¤ h-1, a desorption rate of 0.8 BV ¡¤ h-1, and a mass fraction of 5% NaOH solution, treated with HT-008 ion exchange resin, the average removal rate of COD in wastewater can reach 90%. Reduce the cost of three waste treatment, and recover raw materials such as pyridine, acetone and solvents The test results were used for the actual production of cephalosporin G acid, and good results were obtained.
Key words: cephalosporin G acid; pyridine; resin; adsorption; wastewater treatment
Cephalosporin G acid is a common semi-synthetic cephalosporin intermediate such as cefradine, cephalosporin, cefixime, etc. It is derived from penicillin G through oxidation, ring expansion and rearrangement. The annual domestic demand is about 2 kt. In its production process, a large amount of wastewater is produced (240 kg of wastewater produced by the production of 1 kg of cephalosporin G acid). The wastewater contains a variety of organic solvents and toxic substances, which inhibits the growth of aerobic microorganisms and reduces the efficiency of wastewater biochemical treatment. If effective pre-treatment is performed before the "three wastes" treatment, the solvents and toxic substances are removed, and the COD of the wastewater is reduced. Not only can the costs of the three wastes treatment be reduced, but also the solvents and raw materials can be recovered to achieve resource recycling.
Most domestic chemical methods are used to pretreat the cephalosporin G acid production wastewater, but the treatment cost is high and secondary pollutants are easily generated. This research references and combined with experience, using macroporous resin and ion exchange resin in series two-stage adsorption method to treat cephalosporin G acid production wastewater, compared the effects of different resins on wastewater treatment results, determined the adsorption and desorption process conditions, and This method is applied to industrial production.
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